ATOMNAUT INC. — Department of Defense SBIR Phase II: HR001120S0019-23

ATOMNAUT INC. — SBIR Phase II award from Department of Defense.

Amount
$2,000,000
Agency
Department of Defense · Defense Advanced Research Projects Agency
Program / Phase
SBIR · Phase II
Topic
HR001120S0019-23
Solicitation
HR001120S0019.I
NAICS
Place of performance
CA
Period
2021-08-30 → 2022-08-31

Description

This SBIR Direct to Phase II project scales-up Atom Microscope by Projection (AMP) data production 170x to enable routine, commercially viable, atomic-scale structural biology: position, chemistry, every molecule, in 3D. DNA was first imaged at atomic-scale using early AMP technology (field-ion microscope) in 1971 (1).  Despite this capability demonstration, in the ~50 years to date fewer than 10 biomolecule articles have been published using the approach.  The obstacle is prohibitively slow and error-prone time-to-data, 6 months or more, necessitating an experimental program of years in an effort to achieve scientific repeatability and rigor.