ZYMERON CORPORATION — Department of Health and Human Services SBIR Phase I: 89
ZYMERON CORPORATION — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $300,000
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- 89
- Solicitation
- PHS2021-1
- NAICS
- —
- Place of performance
- NC
- Period
- —
Description
Particle-based Co-delivery of HIV immunogens as Next-generation HIV Vaccines: Tailored immunogens (such as Envs, monomers, native and/or native-like trimers, nucleic acids/RNA such as mRNAs, self-amplifying RNAs) combined with an effective multivalent antigenic display on nanoparticles for delivery may provide a strategy to promote strong and long-lived neutralizing antibody responses against HIV and direct affinity maturation toward HIV neutralizing antibodies. The objective of this contract is to develop a novel nanoparticle delivery system to elicit potent and long-lasting antibody response and broadly neutralizing activity against HIV.