TRANSMURAL SYSTEMS LLC — Department of Health and Human Services SBIR Phase I: 109
TRANSMURAL SYSTEMS LLC — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $399,924
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- 109
- NAICS
- —
- Place of performance
- MA
- Period
- —
Description
SBIR Topic 109, Transcatheter Trileaflet Tricuspid Suture Repair System:Primary and secondary tricuspid valve regurgitation can cause disabling right heart failure, hepatic dysfunction, cardiorenal syndrome, and death.Primary surgical repair or replacement is highly morbid, especially at the advanced stage of typical clinical presentation.Transcatheter repair using marketed and investigational clip-type devices is poorly suited for the trileaflet tricuspid valve.There is substantial unmet need.The goal of this project is to develop a catheter system to achieve a non-surgical off-pump tricuspid valve leaflet repair that allows three or more sutures to reappose three or more tricuspid valve leaflets to repair secondary or primary tricuspid valve regurgitation, sometimes described as “clover-leaf repair.”Under Phase I, the contractor will develop and test a functioning prototype system.