ADVANCED SILICON GROUP, INC. — Department of Commerce SBIR Phase II: None
ADVANCED SILICON GROUP, INC. — SBIR Phase II award from Department of Commerce.
- Amount
- $406,493
- Agency
- Department of Commerce · National Institute of Standards and Technology
- Program / Phase
- SBIR · Phase II
- Topic
- None
- NAICS
- —
- Place of performance
- MA
- Period
- 2019-09-01 → 2021-08-31
Description
Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be used as a cell line-specific platform for biomanufacturers who require custom sensors to measure host cell proteins for their specific cell lines. We will then make a portable system, including both the hardware and software, and bring it to a biomanufacturer’s line to do measurements side by side with ELISA tests. Lastly, we will teach their staff to run measurements using our sensors and system and use their feedback to write a manual for use.