INTELLIGENT FIBER OPTIC SYSTEMS CORP — Department of Health and Human Services SBIR Phase I: NCI

INTELLIGENT FIBER OPTIC SYSTEMS CORP — SBIR Phase I award from Department of Health and Human Services.

Amount
$299,964
Agency
Department of Health and Human Services · National Institutes of Health
Program / Phase
SBIR · Phase I
Topic
NCI
NAICS
Place of performance
CA
Period

Description

Radiation therapy is a widely used primary treatment for multiple malignanciesHoweverphysical dose measurement is not an effective approach as the biological response of different patients or even different types of cancers are very different for the same physical doseMoreoverdiseased tissue and normal organ radiation sensitivities also varyExisting medical devicesphysical dosimetersdo not satisfy all the metrics for assessing biological response to radiation therapyespecially in a point of care mannerIFOS and Stanford University are developing a rapidportableeasy to use and quantitative dose measurement methodcomprising a portable handheld sensor and a novel nanoprobe for rapidreal time in situ imaging of cancerous tissueThe probe is designed to detect Reactive Oxygen and Nitrogen SpeciesRONSgenerated due to radiation and charge particle therapyThe innovation will provide greatly enhanced imaging capabilities to oncologists in radiation treatment monitoring