ENUMERIX, INC. — Department of Health and Human Services SBIR Phase II: 400

ENUMERIX, INC. — SBIR Phase II award from Department of Health and Human Services.

Amount
$1,080,705
Agency
Department of Health and Human Services · National Institutes of Health
Program / Phase
SBIR · Phase II
Topic
400
Solicitation
PA21-259
NAICS
Place of performance
CA
Period
2023-04-01 → 2024-12-31

Description

PROJECT SUMMARY/ABSTRACT Enumerix has developed a cost-effective method to perform high order DNA counting at high precision called direct count PCR (dcPCR). dcPCR uses a spin column method that generates millions of partitions directly into PCR tubes for target amplification, using standard laboratory centrifuge and thermal cyclers, followed by an ultra-rapid method to count up to 1 million copies of DNA directly from the same PCR tube. We have demonstrated that our technology far exceeds the precision of digital PCR, and can perform at a DNA counting range akin to quantitative PCR and next generation sequencing, which makes it a suitable next-generation DNA counting platform. For this proposed Phase II project we plan to further develop our dcPCR platform with the goal to distribute the technology to end-users to replace quantitative PCR and digital PCR.