EKO Devices, Inc. — Department of Health and Human Services SBIR Phase I: NHLBI
EKO Devices, Inc. — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $295,881
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- NHLBI
- Solicitation
- PA17-302
- NAICS
- —
- Place of performance
- CA
- Period
- 2018-07-01 → 2019-12-31
Description
ProjectSummary Abstract ThisSBIRPhaseIprojectwilldevelopadeeplearning basedclinicaldecisionsupportalgorithm foridentifyingaorticstenosisfromheartsoundsrecordedusingtheEkoCoreDigital StethoscopeThisscreeningtoolwillhelptodecreasethenumberofpatientswithsevere asymptomaticaorticstenosisthatremainundertreatedsimplybecausetheconditionisnot diagnosedAuscultationiscommonlythemethodbywhichvalvularheartdiseaseisfirst detectedbutcasesoftenfailtobereferredtoechocardiographyfordiagnosisbecause cliniciansfailtodetectheartmurmursparticularlyinnoisyorrushedenvironmentsToaddress thischallengeEkohaddevelopedtheCoreadigitalstethoscopeattachmentthatcanbeadded in linetoaclinician sexistingstethoscopethatamplifiesheartsoundsandstreamsdigitized phonocardiogramstoasmartphonetabletorpersonalcomputerTherethesignalcanbe analyzedwiththedecisionsupportalgorithmwewilldevelopaspartofthisprojectThespecific aimsofthisstudyaretocollectadatabasewithcondition specificrecordinglabelsto enabledeeplearningforheartsoundsthoughclinicaldatacollectionatUCSFandto developandevaluateadeepconvolutionalneuralnetwork basedalgorithmtrainedonthe databaseByintegratingthisdeeplearningalgorithmintoEko smobileandcloudsoftware platformcurrentlyusedbycliniciansatoverinstitutionsworldwideweanticipatethis algorithmwillenablemoreaccuratescreeningforaorticstenosisleadingtoearlierdiagnosis andbetterpatientoutcomes SBIRProjectNarrative Valvularheartdiseaseandaorticstenosisinparticulararebecomingincreasinglyprevalent manifestationsofpoorcardiovascularhealthinboththedevelopedanddevelopingworldA highly accurateclinicaldecisionsupportalgorithmthatisabletodetectaorticstenosiswill impactpublichealthbyreducingunnecessaryreferralsforechocardiographyandpromoting earlyandaccuratediagnosisinunderservedareaswithlimitedaccesstosubspecialtycare