LUNA INNOVATIONS INCORPORATED — Department of Health and Human Services SBIR Phase I: NIAID

LUNA INNOVATIONS INCORPORATED — SBIR Phase I award from Department of Health and Human Services.

Amount
$299,998
Agency
Department of Health and Human Services · National Institutes of Health
Program / Phase
SBIR · Phase I
Topic
NIAID
NAICS
Place of performance
VA
Period

Description

Proposes to develop a novelstandardized immune assay that improves monitoring of several biomarkerscytokinesassociated with immunologic pathways of AD with the constraint of having a limited amount of biological samplesThis overall goal is supported by the following program objectivesPhase IDemonstrate proof of concept of nanoSPRiSAas a sensitive and efficient technique in assessing cytokines in human serum from AD patientsPhase IIDemonstrate and validate the assay s prototype platform to enable longitudinal measurements in compliance with Good Clinical Laboratory PracticeThe program is organized to demonstrate the technology and to then drive the immunoassay to commercial rollout as soon as possibleThe envisioned product resulting from this technology development program is a nanoSPRiSAassay kit consisting offunctionalized sensing SPRi chips with arrays of capture antibodiespositive controlscytokines of known concentrationbiotinylated detection antibodies andstreptavidin coated nanoenhancer quantum dotsAt the end of the multi phase development effortLuna will have nanoSPRiSAthat is ready for mass production