BACKYARD BRAINS INCORPORATED — Department of Health and Human Services SBIR Phase II: 101

Description

<p>DESCRIPTION provided by applicant Understanding the brain remains a great challenge both to professional neuroscientists and the general public alike The nervous system is extremely complex which is why neural diseases are notoriously widespread and difficult to treat There are two main ways to solve this problem One approach is to fund established scientists to research their particular field of study An alternative way is to invest in the capabilities of future engineers scientists and physicians by providing educational science equipment and compelling experiments that teach principles of neuroscience using simple model organisms A critical barrier to progress with this latter approach has been access to affordable tools and lesson plans To address this need we have developed in our Phase I the andquot SpikerBoxandquot a bio amplifier that is easy to use inexpensive andlt $ portable and can detect and record the spiking activity action potentials of invertebrates such as crickets and cockroaches and the andquot RoboRoachandquot a wireless neural stimulator for investigating insect behavior We have designed easy experiments using these pieces of equipment and have begun deploying them in beta high school test sites In Phase II we now aim to Enhance the learning materials and software to the degree that allows any high school biology teacher with little experience to teach neurophysiology experiments in the classroom Commercialize and deploy the next generation RoboRoach and SpikerBox to allow for a greater versatility in experiments for high school classrooms Commercialize and deploy our andquot OptoGenetics Rig andquot which is a fully portably miniature electrophysiology apparatus enabling optogenetic experiments in fruit flies in high school classrooms As neuroscience is a multi disciplinary field encompassing biology medicine mathematics and engineering our andquot SpikerBoxandquot andquot RoboRoachandquot and andquot Optogeneticandquot kits with their associated learning materials may have the effect of improving performance in STEM related disciplines and inspiring the next generation of scientists and engineers PUBLIC HEALTH RELEVANCE Backyard Brains will commercialize the andquot SpikerBox andquot andquot RoboRoach andquot and andquot Optogeneticandquot kits with associated learning materials and software to allow secondary school students to investigate the living nervous system of insects in the classroom By allowing these students to do what was previously only available in advanced college we aim to inspire the next generation of scientists physicians and engineers as well as accelerate fundamental neuroscience research</p>