BUY TIME MEDICAL INC — Department of Health and Human Services SBIR Phase I: NHLBI

Description

Project Summary Abstract SignificanceAbout one thousand patients suffer cardiac arrest in United States each dayonlyof them surviveTherapeutic hypothermiaTHhas been demonstrated to increase the survival rate and neurological outcome of the cardiac arrest patientsDue to the limitation of existing cooling methodssuch as slow cooling speed and or late induction of hypothermianone of these methods can meet the key requirementsi ethe timing and speed with which the hypothermia to be inducedto gain the optimal benefits of hypothermiaIt results in less thanof eligible patients actually benefiting from hypothermia treatmentBuy Time MedicalBTMinvented a novel cooling device to infuse ice slurrya specially processed micro particulate iceinto the blood vessel of cardiac arrest patient for rapid organ or body coolingPilot large animal experiment demonstrated thatL ice slurry infusion can potentially cool the entire body of an adult human at a rate ofC hrwhich is several folds faster than any other existing cooling methodsBTM s ice slurry cooling device provides a new capability to induce hypothermia by paramedics to meet the timing and speed requirements for optimal outcomeSpecific aimsIn this I Corps training programour three member team will participate in on site Course Kick off and Course Close out sessionsand weekly online Courses to build business model canvasWe will conductinterviews to end users and stakeholders that may influence our device on marketAfter each interviewwe will gradually develop value proposition of our deviceunderstand user case and pain point to position our deviceidentify key activitiesresourcesand partnersand channelsand define cost structureThe results will be incorporated in Commercialization Plan of our phase II proposal and direct its research focusUltimatelythe knowledge will help us to orient our regulatoryreimbursedistributionand market strategies and generate significant socio economic value Project Narrative Mild therapeutic hypothermia has been demonstrated to improve the patient survival rate and neurological outcome of cardiac arrestwhich a leading cause of death in the United StatesOur project is to develop and test a new cooling device that will be able to induce hypothermia earlier and quicker after onset of cardiac arrest and verify its feasibility in animal study using a swine modelI Corps training will significantly help us define commercialization plan that eventually will save lives of cardiac arrest patients and generate socio economic value