CROSSLIFE TECHNOLOGIES INC. — Department of Health and Human Services SBIR Phase I: NIAID

Description

A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus CrossLife Technologies Inc Project Summary Abstract There are unmet needs for nucleic acids new diagnostics that can be applied at the point of care to detect Zika Virus ZIKV infections A highly sensitive simple paper strip molecular test that detects ZIKV at the point of care will be developed The target sequences are amplified using the TARA Template Assisted Rapid Assay technology which is composed of a template dependent chemical transfer reaction with high turnover gold nanoparticle HRP and lateral flow readout The test should be rapid andlt minutes and results in the appearance of colored bands that are detectable by eye A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus CrossLife Technologies Inc RESEARCH andamp RELATED Other Project Information Narrative The rapid spread of Zika virus through the Americas together with the connection of infection with microcephaly and Guillain Barr syndrome have driven this previously overlooked virus into the spotlight The World Health Organization WHO predicts almost four million people could be infected with Zika virus in the Americas in the year