YOUV LABS — Department of Health and Human Services SBIR Phase II: NCI

Description

Shade helps people manage their UV exposure it is a ultraviolet UV monitor with unprecidented accuracyconnected to a mobile application Although it is one of the clearest and most controllable causes of cancer UV exposure can be difficult to estimate due to the importance of combining many rapidly changing factors including intensity shade and use of protective cloting and sunscreen To validate Shade in a short study we enroll a highly susceptable population transplant patients taking immunosupressive drugs Kidney tranplant patients have times higher risk for developing squamous cell carcinoma SCC and once diagnosed they have a far higher rate of developing metasteses and dying SCC develops from precancerous UV triggered actinic keratosis a lesion with remarkably high prevalence in this population This project will accomplish the following recruit transplant patients undergoing regular skin checks provide them with Shade validate that Shade users see a decrease in symptoms and markers of UV exposure by dermatologist observation of actinic keratosis and by a reduction in cyclobutane pyrimidine dimers a biomarker of UV exposure and observe changes in understanding of UV exposure throughcompletion of a UV education survey at the beginning and end of the study