GCFREE, INC. — Department of Health and Human Services SBIR Phase II: NCI
GCFREE, INC. — SBIR Phase II award from Department of Health and Human Services.
- Amount
- $1,499,399
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase II
- Topic
- NCI
- NAICS
- —
- Place of performance
- MA
- Period
- —
Description
Within a tumor there are two main cell types mature cancer cells comprising the majority of a tumor and a small population of especially lethal cancer stem cell CSCs resistant to treatment that can cause cancer relapse Thus novel strategies are needed to target and kill not only the majority of mature cancer cells but also the CSCs in order to achieve long term remissions and potential cures Toward this end Siamab Therapeutics Inc has devised a unique approach to target both mature and CSC components of a tumor using a single therapeutic monoclonal antibody mAb that targets a cancer associated cell surface carbohydrate antigen