Cancer Targeted Technology LLC — Department of Health and Human Services SBIR Phase I: NCI
Cancer Targeted Technology LLC — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $2,000,000
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- NCI
- NAICS
- —
- Place of performance
- WA
- Period
- —
Description
Background Information The Phase II of the contract has four objectives Objective Scale up and analytical characterization of the lead radiotherapeutic agent selected from Phase I Objective Optimization of dose regimen in an animal efficacy model using a PSMA expressing subcutaneous human prostate tumor Objective Maximum Tolerate Dose Study of Lead Lu DOTA PSMA therapeutic agent in normal male rats Objective Assess safety of the radiolabeled lead agent in an IND enabling GLP study in adult male rats Three of these objectives will be pursued by the Subcontractors at University of Pittsburgh