LYNNTECH INC. — Department of Health and Human Services SBIR Phase I: NIEHS

Description

DESCRIPTION provided by applicant Arsenic is found naturally in ground water throughout various parts of the world and has long been an environmental concern because of its toxicity to a large spectrum of organisms even at the parts per billion ppb level A study presented in the Royal Geographic Society Arsenic Conference in reported that over million people in more than countries are affected by arsenic poisoning from drinking water A large number of liver lung and kidney cancer cases as well as dermal conditions such as hyperkeratosis and depigmentation are connected to arsenic ingestion Arsenic is second only to lead as the main inorganic contaminant in the original National Priority List NPL of Superfund sites It is also one of the toxic materials regulated under the Resource Conservation and Recovery Act RCRA Therefore the need exists for arsenic monitoring at Superfund sites RCRA landfills facilities handling arsenic containing wastes and sites The US EPA estimated in that some million people in the USA mostly in the Western states are exposed to arsenic in drinking water at andgt ppb level According to an EPA report EPA R there are approximately community water systems serving about million people where groundwater is used as the source of drinking water supply in the US The treatment plant process control systems in those areas need to be upgraded to monitor the level of arsenic well below ppb to meet the new standards to protect citizens from receiving unsafe drinking water The problem is more severe in developing countries For example in Bangladesh where of citizens million use drinking water from shallow tube wells deaths per year have been reported because of long term ingestion of arsenic contaminated water However a reliable quantitative and easy to use sensor for the determination of arsenic in drinking water especially at low ppb levels is not currently available Conventional methods for the determination of arsenic such as ICP MS and ICP AES are labor intensive time consuming and expensive while colorimetric tests are not quantitative Most of the currently available colorimetric test kits use highly toxic chemicals containing mercury and also produce highly toxic gas arsine during the test To address this need Lynntech proposes to develop a disposable micro cartridge based kit without any toxic metals like mercury or lead that can rapidly quantify arsenic in water using a simple battery operated colorimeter This system will only require the user to pass an aliquot of water sample through a disposable cartridge and take a reading using a low cost handheld colorimeter Additional merits include detection of both oxidation states III and V of arsenic over a wide range ppb ease of handling storage and transportation long shelf life low cost and manufacturability of the cartridges and associated reader PUBLIC HEALTH RELEVANCE Arsenic in drinking water poses a serious health hazard including cancer and severe dermal conditions to tens of millions people around the world However a reliable quantitative and easy to use sensor for determination of arsenic in drinking water especially at low ppb levels is not currently available The goal of the project therefore is to develop a simple sensitive handheld system for rapid quantification of arsenic in water