APTIMA INC — Department of Defense SBIR Phase I: A14-046

Description

Optimal delivery of antibiotics and management of sepsis remains a significant challenge in the critical care setting. Availability of an antibiotic decision support system (DSS) would represent an invaluable asset for healthcare providers, facilitate timely and efficient antibiotic therapies, and lead to improvements in patient safety and outcomes. To address this need, Aptima Inc. and our partners at Analytic Diabetic Systems, LLC, and Ohio State University?s Wexner Medical Center will develop an Intelligent and Directed Antibiotic Decision Support System (IDADSS). IDADSS will provide staff situational awareness of patient state by integrating key data sources (e.g. data from patient monitors) which currently exist outside of a common electronic medical records database, into a common DSS software framework. IDADDS will be designed with a robust yet flexible software architecture enabling portability and ease of integration with military and civilian health care units. Changes in patient physiologic monitoring and institution-specific data sources (e.g., antibiograms) will drive IDADSS?s decision support algorithms to provide alerts and recommendations which provide staff feedback supporting timely and directed antibiotic therapy. IDADSS will encapsulate its data in an intuitive user interface designed with support from end-users to convey information in a way that they can best understand and trust.