BAEBIES, INC. — Department of Health and Human Services SBIR Phase I: DESCRIPTION (provided by applicant): It is reported that up to 40% of neonates undergoing

BAEBIES, INC. — SBIR Phase I award from Department of Health and Human Services.

Amount
$225,000
Agency
Department of Health and Human Services · National Institutes of Health
Program / Phase
SBIR · Phase I
Solicitation
HL14-026
NAICS
Place of performance
NC
Period

Description

DESCRIPTION (provided by applicant): It is reported that up to 40% of neonates undergoing cardiac surgery suffer a major thrombosis event. Pediatric patients who are at increased risk for thrombosis due to either congenital or acquired hypercoagulabilityrequire individualized anticoagulation management. Presence of a thrombophilia influences clinical decision making regarding timing and duration of anticoagulation, particularly in children with venous thrombosis. The duration of therapy is guided by the number of risk factors and thrombophilic conditions. Hypercoagulability panel screening allows risk stratification for therapeutic management. Screening for hypercoagulability is indicated in pediatric patients with a family history of thrombosis, or in those who have suffered a major thrombotic or thromboembolic event. However, a large number of patients develop thrombosis without meeting current criteria for screening. Currently available screening tests are expensive, time-consuming and ordered indi