EUREKA GENOMICS CORPORATION — Department of Agriculture SBIR Phase II: An inexpensive method to track inheritance throughout the genome would be valuable to rese

Description

An inexpensive method to track inheritance throughout the genome would be valuable to researchers, seedstock breeders and eventually to feedlots. The Sparse Genome Scan (SGS) is a new framework for imputing genome wide information and requires a full explanation. SGS is comprised of a set of informative markers distributed sparsely (in order to keep the cost to $20) and evenly throughout the genome. We envision that imputation from the genotypes produced from a SGS can replace most of the other types of genotyping that seedstock breeders currently invest in (parentagetesting or determination, genetic defect testing, qualitative trait testing, and prediction of genetic merit for quantitative traits). With information from SGS, inheritance can be tracked throughout the genome and throughout a large, pedigreed population. The 50K make-up can be imputed to the SGS- genotyped animals, that methodology will be applicable to other animals such as ovein swine and poultry applications