Kestrel Labs Inc — Department of Health and Human Services SBIR Phase II: NHLBI

Description

DESCRIPTION provided by applicant It is a rare event when new and useful medical parameters can be added to the suite of monitoring and diagnostic tests available in a clinical setting Of particular importance is the ability to measure crucial physiological parameters or analyses in a continuous and noninvasive manner evidenced by the importance of noninvasive vital signs monitoring because it reduces expense eliminates delays in diagnosis and removes the potential for exposure to blood borne pathogens The project for which this SBIR Grant proposal is being submitted will continue the work towards a new patient monitor capable of accurate noninvasive and continuous measurements of total hemoglobin the The measurement of total hemoglobin is a crucial and frequently performed blood test used in nearly all areas of healthcare The accurate measurement of this parameter is particularly important for patients potentially requiring a transfusion receiving rapid administration of fluids undergoing surgical procedure or having experienced trauma that has resulted in significant blood loss Total hemoglobin must also be measured for anemia screening prior to blood donation The proposed new monitor would look much like conventional pulse dosimeter the ubiquitous vital signs monitor that has been in clinical use since the s and which uses a clothespin like sensor to andquot shineandquot red and infrared light through the finger and report a measure of the oxygen level in the arterial blood And in fact the ultimate goal of the product development effort that would follow this feasibility study will be the integration of total hemoglobin measuring capabilit into a pulse dosimeter Successful completion of the proposed grant work will complete the next important steps towards the creation of this new medical monitor This work will prove that the high measurement precision provided by the use of narrow band lasers can make possible accurate noninvasive measurement of the on human subjects over a clinically relevant the range The continuation of this work into the development of a full commercial version will then lead to a regulatory submission for FDA k clearance to allow the marketing and sale of this device to the medical community Availability of a noninvasive total hemoglobin monitor will help diagnose anemic patients sooner and contribute to the judicious use of blood transfusions all with less pain or risk of infection while reducing the time burden on caregivers and costs to the healthcare system It could also eliminate the need for the somewhat painful finger sticks associated with blood donation PUBLIC HEALTH RELEVANCE An important part of medical care is the use of tests that help clinicians diagnose disease or other medical conditions but often these tests require that blood or other samples be drawn from the body and sent to a central hospital laboratory The proposed work has an ultimate goal of creating a monitor that can measure the levels of hemoglobin the oxygen carrying protein in a patientandapos s blood without the need to draw a blood sample This will ease patient distress and risk of infection speed diagnosis and result in improved patient outcomes and reduced healthcare costs