MASSTECH, INC. — Department of Health and Human Services SBIR Phase I: DESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of a
MASSTECH, INC. — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $164,916
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Solicitation
- PA13-234
- NAICS
- —
- Place of performance
- MD
- Period
- —
Description
DESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of atmospheric pressure chemical ionization (APCI) in tandem mass spectrometry (MS/MS) will have a profound impact on its applications to the entire analytical field of characterization of drugs, metabolites, lipids, steroids, etc. A broad applicability of APCI-based MS analysis makes it a unique analytical tool specifically targeting trace amounts of many chemical and biological substances. We plan to build a novel APCI ion source based on atmospheric dielectric barrier discharge (DBD) to significantly improve efficiency and specificity of ACPI-MS based detection method. PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: Atmospheric pressure ionization is a broadly used technique in the analysis of complex chemical and biological samples providing reliable identification of drugs, disease-specific metabolites, steroids, antibiotics, etc. utilizing mass-spectrometers. We plan to develop a novel APCI source that