SIMPHOTEK, INC. — Department of Health and Human Services SBIR Phase I: DESCRIPTION (provided by applicant): Photodynamic therapy (PDT) is used for treating a var
SIMPHOTEK, INC. — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $225,000
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Solicitation
- PA13-234
- NAICS
- —
- Place of performance
- NJ
- Period
- —
Description
DESCRIPTION (provided by applicant): Photodynamic therapy (PDT) is used for treating a variety of medical conditions including cancer. Even after many years of PDT research and the large-scale use of PDT treatments by physicians, there are many aspects ofPDT, such as quantitative predictions for diffusive light propagation and the kinetics of the light-material interactions, that are not well understood. This can lead to a large variation in treatment results In particular, the dosimetry for treatments ischallenging and it is difficult to determine the lasr light energies and the photosensitizer (PS) concentrations that are optimal. In this Phase I SBIR, Simphotek (prime institution), Tech-X (subaward institution) and University of Pennsylvania School of Medicine, i.e. UPenn (subaward institution) will investigate the feasibility of experimentally (UPenn) and computationally (Simphotek/Tech-X) guiding novel and easy-to-use mathematical and numerical methods for PDT. The software product(s) that result