ELECTRONIC BIOSCIENCES, INC. — Department of Defense SBIR Phase II: This Small Business Innovation Research project will develop a non-animal based in vitro a
ELECTRONIC BIOSCIENCES, INC. — SBIR Phase II award from Department of Defense.
- Amount
- $999,988
- Agency
- Department of Defense · Office for Chemical and Biological Defense
- Program / Phase
- SBIR · Phase II
- Solicitation
- 2011.1
- NAICS
- —
- Place of performance
- CA
- Period
- 2012-05-24 → 2014-09-23
Description
This Small Business Innovation Research project will develop a non-animal based in vitro assay for determining the efficacy of Botulinum (BoNT) neutralizing therapeutics. New technologies are currently needed in order to facilitate the development and approval of BoNT vaccines and therapies and reduce the number of vertebrate animals used in medical testing. In Phase 1 of this project, the feasibility of the proposed system was demonstrated. During Phase 2, a complete working prototype will now be built, tested and validated against the standard mouse lethality neutralization (MLN) assay. Electronic BioSciences"proposed system will be capable of monitoring the complete neutralizing mechanism of therapies to all seven BoNT serotypes, making rapid, non-animal based neutralization efficacy testing possible.