Electrical Geodesics, Inc. — Department of Defense SBIR Phase I: The purpose of the proposed work is to demonstrate the feasibility of a novel instrument f

Description

The purpose of the proposed work is to demonstrate the feasibility of a novel instrument for multi-channel nuclear Magnetic Resonance Imaging (MRI) at ultra-low field (ULF). The instrument will overcome issues involved with conventional MRI systems use in combat casualty care. It will also provide direct measurement of neurophysiological activation dynamics by magnetoencephalography (MEG) and will be compatible with other imaging modalities like dense array EEG and NIRS. The system will be focused on the assessment of Traumatic Brain Injury, an increasingly important class of combat casualty and source of morbidity. The instrument will be designed to satisfy a demanding slate of performance, system design, operational and siting requirements to facilitate transport and allow operation at Combat Support Hospitals. We propose to develop the first of a new generation of clinical and research systems, combining the technologies of MEG and MRI into a single instrument with revolutionary capabilities for imaging brain structure and function. We term this hybrid instrument neurological MRIneuMRI. Although this project focuses on military requirements, if successful the system is likely to have sweeping implications for scientific investigation and civilian medical practice.