Adjuvax LLC — Department of Health and Human Services SBIR Phase I: 106
Adjuvax LLC — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $600,000
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- 106
- Solicitation
- PHS-2022-1
- NAICS
- —
- Place of performance
- AL
- Period
- —
Description
AS01b (composed of the molecules QS-21 and MPL) is a powerful adjuvant best known for being a component of the FDA-approved Shingrix vaccine. Despite its successful track-record as an effective adjuvant, accessibility to AS01b as an adjuvant for use in novel vaccines is a concern due to the limited nature of the saponin molecule QS-21. The awardee seeks to address this problem by developing a mimic of AS01b by replacing QS-21 with a novel saponin molecule.