MOLECULAR EXPRESS, INC — Department of Health and Human Services SBIR Phase I: NIAID
MOLECULAR EXPRESS, INC — SBIR Phase I award from Department of Health and Human Services.
- Amount
- $599,983
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- NIAID
- NAICS
- —
- Place of performance
- CA
- Period
- —
Description
This proposal aim to develop a VesiVaxplatform based liposomal vaccine that can co formulate the HIV antigenHIV Env gpAwith various immunotimulatory adjuvant moleculesIAMsThe IAMs that we will formulate with the antigen includeslipidated tucaresolmuramyl tripeptide phosphatidylethanolaminePam CAGmonophosphoryl lipid AdsRNAandcyclic dinucleotidesThe formulations will be evaluated in miceand selected formulations with the highest specific antibody titers will be optimized for antigen and adjuvant doses