Department of Health and Human Services SBIR/STTR Awards & Open Topics
The Department of Health and Human Services has made 16,335 SBIR/STTR awards totaling $10,466,145,484. Its top technology areas include Human Performance & Medical, Artificial Intelligence/ML, Sensors & Sensor Fusion, Cybersecurity, and Communications/Networking. There are currently 16 open or upcoming topics.
- 16,335 SBIR/STTR awards
- $10,466,145,484 total on record
- 16 open topics
Who wins here
Top recipient firms by total award dollars on record for Department of Health and Human Services.
- SANARIA INC. — $57,916,904
- Epicypher, Inc. — $48,732,885
- PHYSICAL SCIENCES INC. — $43,786,776
- KITWARE INC — $41,257,204
- MICROBIOTIX, INC. — $40,862,670
Match your capability to open topics → · Competitive intelligence hub →
Awards by year
- 4 in 2026
- 16 in 2025
- 15 in 2024
- 1,148 in 2023
- 1,154 in 2022
pWin signals — Phase mix & conversion
Firm-level Phase I→II conversion proxy and average award size by phase for Department of Health and Human Services. A capture signal, not an official SBA rate.
- 37.5% Phase I→II firm conversion
- Phase I 11,881 awards
- Phase II 4,429 awards
Where Department of Health and Human Services spends in tech
Compare conversion across agencies → · Match your capability to open topics →
Open & upcoming topics
See all open Department of Health and Human Services topics →
Recent awards
Spoke pages in this Department of Health and Human Services cluster — open any award for phase, amount, and competitive context.
| Recipient | Agency | Amount | Program | Start |
|---|---|---|---|---|
| HLTH, INC. | Department of Health and Human Services | $80,000 | STTR | 2026-09-28 |
| BHI MANAGEMENT INC | Department of Health and Human Services | $2,295,326 | STTR | 2026-09-28 |
| RESEARCH TRIANGLE INSTITUTE | Department of Health and Human Services | $531,049 | STTR | 2026-09-22 |
| RESEARCH TRIANGLE INSTITUTE | Department of Health and Human Services | $499,459 | STTR | 2026-09-21 |
| SYZONC, INC | Department of Health and Human Services | $299,878 | SBIR | 2025-09-29 |
| MERLIN BIOTECH INC | Department of Health and Human Services | $300,000 | SBIR | 2025-09-22 |
| TENACI-T THERAPEUTICS LLC | Department of Health and Human Services | $297,621 | SBIR | 2025-09-17 |
| NOVOMEDIX LLC | Department of Health and Human Services | $2,977,013 | SBIR · Phase II | 2025-09-15 |
| ASO THERAPEUTICS, INC. | Department of Health and Human Services | $299,991 | SBIR | 2025-09-15 |
| CLOVERLEAF BIO, INC. | Department of Health and Human Services | $300,000 | SBIR | 2025-09-15 |
| TIPPINGPOINT BIOSCIENCES, INC. | Department of Health and Human Services | $300,000 | SBIR | 2025-09-15 |
| BIOLOGICAL MIMETICS, INC. | Department of Health and Human Services | $1,498,641 | SBIR · Phase II | 2025-09-15 |
FAQ
How many SBIR/STTR awards has Department of Health and Human Services made?
Department of Health and Human Services has 16,335 SBIR/STTR awards worth $10,466,145,484 in the records SBIR Signal tracks from USASpending and SBIR.gov.
Does Department of Health and Human Services have open SBIR/STTR topics right now?
Department of Health and Human Services currently has 16 open or upcoming SBIR/STTR topic(s) you can bid on. See the opportunities feed for deadlines.
What technology areas does Department of Health and Human Services fund?
Top technology areas in the award record include Human Performance & Medical, Artificial Intelligence/ML, Sensors & Sensor Fusion, Cybersecurity, Communications/Networking.
How do I find the best Department of Health and Human Services topic for my company?
Paste your capability statement into the free SBIR capability matcher and it ranks every open topic by fit, or run the free readiness scorecard to see how competitive you are before you bid.