SACHI BIOWORKS, INC. — National Aeronautics and Space Administration SBIR Phase I: H8

Description

While the space is nominally considered a ldquo;harshrdquo; environment for sustaining life due to its atmosphere, microgravity, and exposure to intense galactic cosmic rays (GCR), causing adverse health effects like accelerated aging, DNA damage, tissue damage, and disease, it also offers unique opportunities for development and screening of therapeutic modalities that can immensely benefit therapeutic development activities for terrestrial applications. Another advantage the unique space environment offers is the effect of microgravity enables facile formation of human organoids 3D in vitro models that exquisitely mimic the complexity of our tissues and organs and provide a practical alternative to whole-organism studies in human and can be used to study various pathophysiological phenomena on Earth, for deep space manned missions, and developing personalized medicine. Sachi Bioworks will team up with Space Tango for accelerating the development of therapeutics for neurodegeneration, cancer treatment, and cardiovascular diseases.