H NU Photonics LLC — Department of Defense SBIR Phase II: HR001120S0019-27
H NU Photonics LLC — SBIR Phase II award from Department of Defense.
Phase II SBIR prototype / development signal
- Phase II is where Department of Defense funds deeper R&D after feasibility. Incumbents with Phase II history are serious competitors on adjacent topics.
- Use this award as past-performance context and to map customer organizations for STRATFI/TACFI-style transition planning.
- At $1,748,546, this is a large obligation for typical SBIR Phase sizing — worth reviewing for scope breadth and teaming opportunity.
- Topic code HR001120S0019-27 links this award to a solicitation family — search the same topic stem for incumbents and recompete timing.
- Amount
- $1,748,546
- Agency
- Department of Defense · Defense Advanced Research Projects Agency
- Program / Phase
- SBIR · Phase II
- Topic
- HR001120S0019-27
- Solicitation
- HR001120S0019.I
- NAICS
- —
- Place of performance
- HI
- Period
- 2022-07-13 → 2024-08-15
Description
The proposed FLASH-CSI is a disruptive technology designed to be quickly implemented into existing, remote, or mobile production facilities for in-line sterility testing of manufactured biological products. With savings of time and cost, and utilizing minimal sample volumes, this fully sealed aseptic testing platform is expected to outperform current methods and return quantitative results within minutes. FLASH-CSI is poised to become a broadly useful analytical instrument fulfilling several DoD and market needs. Bioreactors output nucleic acid or protein products that are complex macromolecular fluids. As such, it becomes challenging to discern whether sparse contaminant entities reside within this complex background. Traditional mechanisms of detecting microbe contamination require time consuming and destructive methods with reagents, assay and plating procedures. The COVID-19 pandemic has highlighted the need for the Department of Defense (DoD) to optimize production of life-saving therapeutics and vaccines. HNu Photonics specializes in the creation, fabrication, and implementation of innovative technologies at the forefront of life science research on the International Space Station. The proposed work will harness our existing space-based technology (automated microscopy and microfluidics) and continue the research and development efforts begun in Phase I delivering optimized performance of FLASH-CSI across different uniquely identifiable contaminants. FLASH-CSI will complement DoD efforts by rapidly detecting contaminates within biological processes (antibody or vaccine production) with a non-invasive, triple redundant optical detector.