NEMAMETRIX, INC — Department of Health and Human Services SBIR Phase I: 100
NEMAMETRIX, INC — SBIR Phase I award from Department of Health and Human Services.
Phase I SBIR feasibility signal
- Phase I awards fund proof-of-concept work. For capture teams, they mark early interest from Department of Health and Human Services in a technical approach.
- Watch for Phase II follow-ons from the same firm/topic family — that conversion path is where budgets and transition pressure rise.
- Obligated amount $464,655. Cross-check similar awards in the same agency and technology tags for going-rate context.
- Topic code 100 links this award to a solicitation family — search the same topic stem for incumbents and recompete timing.
- Amount
- $464,655
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- 100
- Solicitation
- PAR19-265
- NAICS
- —
- Place of performance
- OR
- Period
- 2022-08-15 → 2023-08-14
Description
Summary: Unlike C. elegans and mice, methods for cold storage of zebrafish lines are lacking in the marketplace. We propose the use of environmental and gene c factors to enable cold storage of viable embryos at frozen or near freezing condi ons. In Aim 1 we will explore the use of transient protein expression to produce proteins associated with anhydrobio c status. In Aim 2 we explore the induc on of genes involved in diapause in killifish as a mechanism to promote cold-storage survival. In Aim 3, we will look at combina ons of gene c and environmental factors that promote reanima on of zebrafish embryos from cold storage. Achievement of any one of these aims that result in high viability yields from cold storage can then be developed in Phase II as a gene cally integrated line, which can then be broadly commercialized as a product or service to aid researchers in their biobanking efforts with their zebrafish lines.