QOOLABS INC — Department of Health and Human Services SBIR Phase I: 107
QOOLABS INC — SBIR Phase I award from Department of Health and Human Services.
Phase I SBIR feasibility signal
- Phase I awards fund proof-of-concept work. For capture teams, they mark early interest from Department of Health and Human Services in a technical approach.
- Watch for Phase II follow-ons from the same firm/topic family — that conversion path is where budgets and transition pressure rise.
- Obligated amount $600,000 is consistent with substantial Phase II-scale effort; compare to related awards from the same agency.
- Topic code 107 links this award to a solicitation family — search the same topic stem for incumbents and recompete timing.
- Amount
- $600,000
- Agency
- Department of Health and Human Services · National Institutes of Health
- Program / Phase
- SBIR · Phase I
- Topic
- 107
- Solicitation
- PHS-2022-1
- NAICS
- —
- Place of performance
- CA
- Period
- —
Description
Swine is a useful animal model for studying human health and diseases. Particularly, swine is currently preferred candidate species as the source animal for xenotransplantation. However, the usefulness of pig for biomedical research has been constrained by the lack of reagents targeting immune markers involved in tissue/organ rejection. The objectives of this proposal are to generate rabbit monoclonal antibodies to selected swine immune markers that are related to xenotransplantation and to characterize the produced antibodies to demonstrate their reactivity with the appropriate swine immune cell subsets. Successful production of these antibodies will generate useful tools to promote pre-clinical biomedical research especially xenotransplantation investigations.