INNOVITAL SYSTEMS INC — Department of Defense SBIR Phase II: DHP17-007
INNOVITAL SYSTEMS INC — SBIR Phase II award from Department of Defense.
Phase II SBIR prototype / development signal
- Phase II is where Department of Defense funds deeper R&D after feasibility. Incumbents with Phase II history are serious competitors on adjacent topics.
- Use this award as past-performance context and to map customer organizations for STRATFI/TACFI-style transition planning.
- Obligated amount $999,955 is consistent with substantial Phase II-scale effort; compare to related awards from the same agency.
- Topic code DHP17-007 links this award to a solicitation family — search the same topic stem for incumbents and recompete timing.
- Amount
- $999,955
- Agency
- Department of Defense · Defense Health Program
- Program / Phase
- SBIR · Phase II
- Topic
- DHP17-007
- Solicitation
- 17.1
- NAICS
- —
- Place of performance
- MD
- Period
- 2018-08-27 → 2021-01-26
Description
Accurateintravascularvolumeassessment improves the detection of hemorrhageand hypovolemiaand facilitates decision-makingrelativeto resuscitation,surgery,and selection of higher level ofmedical care. Non-invasiveassessment techniquesare particularly important in thefield. Currentapproachesand devices do not have broad utilityand availability. Duringthe PhaseIeffort, the project team developed alow-profile phonocardiography transducerand state-of-the-art segmentation algorithm to provides insight into cardiaccycletimeintervals (CCTI’s)and, thereby, trends in intravascularvolume. In parallel, internally-funded, IRB-approved clinical studies wereconducted,acquiring non-invasive measurements on subjects in hemorrhageand hypovolemicconditionsas simulated by lower body negative pressureand hemodialysis. Changes of CCTI’s with smallamounts of hypovolemia(~2%) were demonstrated as wellas the progression to largervolumeloss with enhanced contractility. This trendingcan beimmensely useful to theclinician. Largerclinical studies will becompleted in the PhaseIIeffort including blood donorsasanother hemorrhagemodel. Datareduction from theseclinical studies will be used to identifyaset of measurement modalitiesand metrics foravolumeassessment system. Thesensingand processing hardware will beintegrated with data analysisalgorithms onto a benchtop prototypesystem.