BLACKROCK MICROSYSTEMS, INC — Department of Health and Human Services SBIR Phase I: 102

Description

DESCRIPTION provided by applicant The objective of this proposal is to design develop and validate a commercially viable andquot human useandquot smart channel macro andamp micro ECoG microsystem with integrated recording stimulation and impedance measuring capabilities for epilepsy monitoring The microsystem comprises of a state of art microelectronic signal processing component linked to a macro andamp micro integrated ECoG grid via a thin highly flexible bio compatible micro ribbon cable on one end and a single percutaneous flexible cable andquot pigtailandquot on the other end The custom multiplexing ASIC electronics is capable of channel recordings at bit resolution and has fast settle capability for stimulation option and patient safety circuitry The component is contained on a printed circuit board and is encapsulated with Parylene C and Silicone The encapsulated microelectronic component unit is encased in a titanium case and resides subcutaneously between the skin and the skull The integrated microsystem would have unique andquot snow flakeandquot shape grid design containing alternate rows of macro and micro channels The phase I would target a short term goal of developing bench testing and validating in adult sheep model the complete implantable ECoG microsystem that can be translated to research and clinical lab in the shortest time frame PUBLIC HEALTH RELEVANCE The objective of this proposal is to design develop and validate a commercially viable andquot human useandquot thin film polymer based smart channel macro andamp micro integrated ECoG array system for epilepsy monitoring